Epigenetics

Affymetrix, Agilent and Illumina offer solutions for studies of gene regulation.

The Affymetrix and Agilent platforms provide tiling arrays for a number of species. Tiling arrays can be used for either chIP-on-chip or transcript mapping experiments.

ChIP-on-chip

Chromatin immunoprecipitation coupled with high-density tiling arrays (ChIP-on-chip) is a powerful technique for identifying transcription factor binding sites, sites of histone modification, DNA methylation and other regulatory elements.

For different options and format please find more information at the Affymetrix and Agilent sites below:

Transcript Mapping

Transcript mapping with Tiling Arrays enables you to interrogate genomes at regular intervals, including both annotated and unannotated regions. With their unbiased approach to genome interrogation, GeneChip Tiling Arrays are an important tool in discovering novel transcripts and building newer, more up-to-date annotations.

Illumina Methylation Analysis

Methylation profiling with BeadArray technology allows researchers to analyze the effects of aberrant methylation (either hyper- or hypomethylation) for a variety of applications.

Illumina has developed a robust methylation profiling platform that provides quantitative methylation measurement at the single-CpG-site level, providing the highest resolution for understanding epigenetic changes.